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This study aims to evaluate the prevalence of hepatitis E virus infection among pregnant women in Tunisia.

May 21, 2026PathogensOpen Access

Prevalence of Hepatitis E Virus Infection Among Pregnant Women in Tunisia: Findings from a Large Cohort Study

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Cohort study evaluates HEV infection prevalence in pregnant women, highlighting low infection rates in Tunisia.

This study aims to evaluate the prevalence of hepatitis E virus infection among pregnant women in Tunisia.
Cohort study design with 891 pregnant women enrolled between 2021 and 2023.
Serum samples screened for HEV antibodies and RNA using ELISA tests and molecular assays.
Statistical analyses were performed using SPSS 21.0 and EPISTAT version 7.2.6.
Overall seroprevalence of HEV infection was 3.82% based on anti-HEV IgG detection.
Higher seroprevalence observed in women older than 30 years (p < 0.05).
Viral RNA was detected in one of 51 women with composite outcomes via real-time RT-PCR.

Ayouni et al. (2026) studied this question.

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