Key result
Among pregnant women in Gabon, the seroprevalence of hepatitis E virus was 7.1% in HIV-1-infected and 5.0% in HTLV-1-infected women, and past HEV exposure was associated with a significantly higher HIV-1 viral load.
Population
243 pregnant women in Gabon, Central Africa, infected with HIV-1 or HTLV-1, mean age 28.2 years.
Design
Cross-sectional
Authors
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Past HEV exposure may flag higher HIV-1 loads in pregnant women; leaves open causality and screening value in endemic areas.
Cross-Sectional (n=243)
No
Absolute Event Rate: 7.1% vs 5%
p-value: p=NS
HIV-1-infected pregnant women with high viral loads may be at increased risk for HEV acquisition or severe infection in endemic areas.
Caron et al. (2012) conducted a cross-sectional in HIV-1 or HTLV-1 infection in pregnancy (n=243). HIV-1 infection vs. HTLV-1 infection was evaluated on Prevalence of IgG antibodies to HEV (p=NS). Among pregnant women in Gabon, the seroprevalence of hepatitis E virus was 7.1% in HIV-1-infected and 5.0% in HTLV-1-infected women, and past HEV exposure was associated with a significantly higher HIV-1 viral load.
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