This report demonstrates the use of sodium borohydride to enable cyclization in acrylamides, suggesting a novel application for this reducing agent.
Herein, we report that NaBH4 facilitates an unusual reductive cyclization of N-(2-iodoaryl)acrylamide derivatives to afford oxindoles without the need for external initiators. While other hydride donors failed to achieve this...
No takes yet. Share an insight, caveat, or question.
Sihag et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: