Hypertension, lipoprotein(a), and apolipoprotein A-I as risk factors for stroke in the Chinese.
Key result
A history of hypertension, high serum lipoprotein(a), and low apolipoprotein A-I were independent risk factors for stroke, with hypertension having a 24% attributable risk in patients ≥60 years.
Why the study?
Are hypertension, lipoprotein(a), and apolipoprotein A-I independent risk factors for stroke in a Chinese population?
Population
608 Chinese individuals, comprising 304 consecutive patients with acute stroke and 304 age- and sex-matched…
Design
Case-control
Authors
Discussion
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Implication
Should not yet alter stroke prevention in Chinese adults; extends observational data on these factors but remains hypothesis-generating.
Study Design
Type
Case-Control (n=608)
Structured PICO
Are hypertension, lipoprotein(a), and apolipoprotein A-I independent risk factors for stroke in a Chinese population?
P
Population
608 Chinese individuals, comprising 304 consecutive patients with acute stroke (cerebral infarction, lacunar infarction, or intracerebral hemorrhage) and 304 age- and sex-matched controls.
C
Comparator
304 age- and sex-matched controls
O
Outcome
Risk factors for acute strokehard clinical
Hypertension, elevated lipoprotein(a), and low apolipoprotein A-I are independent risk factors for acute stroke in the Chinese population.
Cite This Study
Woo et al. (1991) conducted a case-control in Acute stroke (n=608). Risk factors (hypertension, lipoprotein(a), apolipoprotein A-I) vs. Age- and sex-matched controls was evaluated on Acute stroke. A history of hypertension, high serum lipoprotein(a), and low apolipoprotein A-I were independent risk factors for stroke, with hypertension having a 24% attributable risk in patients ≥60 years.