Key result
Late potentials on signal-averaged ECG were present in 78% of Chagas' disease patients with sustained ventricular tachycardia versus 31% without SVT in the absence of bundle branch block (p<0.001).
Why the study?
Does the presence of late potentials on Signal Averaged ECG correlate with sustained ventricular tachycardia in patients with chronic Chagas' heart disease?
Population
192 patients with chronic Chagas' heart disease (CCD), mean age 42.9 years, 96 males.
Design
Cohort
Authors
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May aid VT risk stratification in Chagas cardiomyopathy without BBB; hypothesis-generating and requires prospective validation.
Observational (n=192)
Does the presence of late potentials on Signal Averaged ECG correlate with sustained ventricular tachycardia in patients with chronic Chagas' heart disease?
Absolute Event Rate: 78% vs 31%
p-value: p=<0.001
Late potentials on signal-averaged ECG are significantly associated with sustained ventricular tachycardia in patients with chronic Chagas' heart disease, particularly in those without bundle branch block.
Moraes et al. (1995) conducted an observational in chronic Chagas' heart disease (n=192). Signal Averaged ECG was evaluated on Presence of late potentials in patients without bundle branch block (p=<0.001). Late potentials on signal-averaged ECG were present in 78% of Chagas' disease patients with sustained ventricular tachycardia versus 31% without SVT in the absence of bundle branch block (p<0.001).
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