Key result
Diltiazem improved myocardial blood flow to the ischaemic zone, reduced LVEDP, and decreased the incidence of ventricular fibrillation in a new model of multivessel myocardial ischaemia.
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Should not change practice; extends preclinical data on diltiazem in multivessel ischaemia models.
Szekeres et al. (1985) studied Myocardial ischaemia. Diltiazem was evaluated on Myocardial blood flow, LVEDP, electrical activation, ST-segment elevation, and arrhythmias. Diltiazem improved myocardial blood flow to the ischaemic zone, reduced LVEDP, and decreased the incidence of ventricular fibrillation in a new model of multivessel myocardial ischaemia.
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