Why the study?
Does simultaneous multisite mapping identify potential drivers of human atrial fibrillation?
Population
24 patients with atrial fibrillation (12 persistent), mean age 61+/-10 years
Design
Cross-sectional, Blinded analysis for mapping ablation lesions to driver sites
Key result
Simultaneous multisite mapping identified potential AF drivers in 11 of 24 patients, located near pulmonary veins in paroxysmal AF but not in persistent AF (P<0.05).
Authors
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Simultaneous multisite mapping may detect AF drivers with type-specific locations; leaves open whether targeting improves ablation outcomes.
Observational (n=24)
Blinded analysis
Does simultaneous multisite mapping identify potential drivers of human atrial fibrillation?
p-value: p=<0.05
Simultaneous multisite mapping identifies potential AF drivers near pulmonary veins in paroxysmal AF, but at the coronary sinus and LA roof in persistent AF.
Krummen et al. (2009) conducted an observational in Atrial fibrillation (n=24). Simultaneous multisite mapping vs. Sequential mapping was evaluated on Evidence for potential AF drivers (p=<0.05). Simultaneous multisite mapping identified potential AF drivers in 11 of 24 patients, located near pulmonary veins in paroxysmal AF but not in persistent AF (P<0.05).
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