Key result
Recent applications of molecular and cell biology techniques to animal models and human myocardial tissue are providing new insights into the cellular mechanisms of progression to heart failure.
Population
Animal models of cardiac hypertrophy and failure, genetically engineered mice, and human myocardial tissue…
Design
Review
Authors
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Advances mechanistic insights in heart failure without clinical application; leaves open translation to targeted therapies.
Molecular and cell biology techniques applied to animal models and human tissue are advancing the understanding of the cellular pathophysiology of heart failure.
Wagoner et al. (1996) conducted a review in Congestive heart failure. Recent applications of molecular and cell biology techniques to animal models and human myocardial tissue are providing new insights into the cellular mechanisms of progression to heart failure.
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