Wall Thickness and Diastolic Properties of the Left Ventricle
Key result
Left ventricular posterior wall thickness at end diastole strongly correlated with effective diastolic stiffness (r=0.85, P<0.001), independent of left ventricular mass.
Population
24 patients with various forms of heart disease
Design
Cross-sectional
Authors
Discussion
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Implication
LVPWd may aid noninvasive diastolic stiffness estimation in echo; leaves open prognostic and therapeutic implications.
Study Design
Type
Observational (n=24)
Structured PICO
P
Population
24 patients with various forms of heart disease
O
Outcome
Correlation between LV posterior wall thickness at end diastole (hp) and effective diastolic stiffness (S), normalized stiffness (SN), and LV end diastolic pressure (LVEDP)surrogate
Main Result
Effect estimate: r = 0.85
p-value: p=<0.001
Left ventricular posterior wall thickness is an important determinant of diastolic stiffness and pressure, predicting diastolic stiffness independent of the presence of LV hypertrophy or increased LV mass.
Cite This Study
Grossman et al. (1974) conducted an observational in Various forms of heart disease (n=24). Left ventricular posterior wall thickness at end diastole (hp) was evaluated on Correlation between LV posterior wall thickness (hp) and effective diastolic stiffness (S) (r = 0.85, p=<0.001). Left ventricular posterior wall thickness at end diastole strongly correlated with effective diastolic stiffness (r=0.85, P<0.001), independent of left ventricular mass.