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October 1, 1971Circulation

Pathologic Changes in Aortic-Coronary Arterial Saphenous Vein Grafts

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Key result

Saphenous vein grafts in place for ≥3.5 months consistently developed lesions, with 5 of 6 grafts showing intimal fibrous proliferation resulting in near or complete luminal occlusion.

Population

Segments of saphenous vein used as a graft between the aorta and a coronary artery in the surgical treatment…

Design

Case_series

Follow-up

3.5 months or longer

Authors

ZVZeev VlodaverUniversity of MinnesotaJEJesse E. EdwardsUniversity of Southern California

Discussion

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Implication

May prompt early SVG surveillance post-CABG; leaves open incidence, mechanisms, and preventability in larger cohorts.

Study Design

Type

Observational

Structured PICO

P
Population
Segments of saphenous vein used as a graft between the aorta and a coronary artery in the surgical treatment of coronary atherosclerosis
I
Intervention
Saphenous vein graft
O
Outcome
Pathologic changes and lesions in the saphenous vein graftsurrogate

Saphenous vein grafts exposed to arterial pressure can rapidly develop intimal fibrous proliferation leading to near or complete occlusion within months.

Cite This Study

Vlodaver et al. (1971) conducted an observational in Coronary atherosclerosis. Aortic-coronary arterial saphenous vein grafts was evaluated on Pathologic changes in saphenous vein grafts. Saphenous vein grafts in place for ≥3.5 months consistently developed lesions, with 5 of 6 grafts showing intimal fibrous proliferation resulting in near or complete luminal occlusion.

synapsesocial.com/papers/6a0eb2bd1c5e2d2319f9be08https://doi.org/10.1161/01.cir.44.4.719
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Determinants of Blood Flow in Aortic-Coronary Saphenous Vein Bypass Grafts1970 · 37 citations
  2. 2Myocardial Revascularization With Internal Mammary Artery Implantation1969 · 36 citations
  3. 3Selective Revascularization of the Myocardium by Internal-Mammary-Artery Implant1966 · 78 citations
  4. 4Coronary Endarterotomy with Patch-Graft Reconstruction1965 · 92 citations