Key result
Aortocoronary saphenous vein bypass grafting has a 10-year patency rate of 50%-60%, with late graft failure driven by rapid, diffuse atherosclerosis that makes venous plaques vulnerable to rupture.
This review highlights the distinct, rapid pathophysiology of saphenous vein graft atherosclerosis compared to arterial disease, explaining the high rates of late graft failure.
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Supports arterial graft preference where feasible; leaves open targeted SVG atherosclerosis prevention trials.
Hassantash et al. (2008) conducted a review in Aortocoronary saphenous vein bypass graft disease. Aortocoronary saphenous vein bypass grafting has a 10-year patency rate of 50%-60%, with late graft failure driven by rapid, diffuse atherosclerosis that makes venous plaques vulnerable to rupture.
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