Key result
High dominant frequency patterns exhibit ~38% lower temporal standard deviation and higher organization than non-dominant patterns.
Why the study?
Identifying catheter ablation targets in persistent AF remains challenging, and the spatiotemporal behavior and recurrence of dominant frequency patterns are not fully understood.
Population
10 patients undergoing persAF HDF ablation
Comparison
Automated pattern recognition algorithm on non-contact mapping before and after ablation
Follow-up
Up to 5 min before and after ablation
Authors
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May guide ablation to stable high-DF sites in persistent AF; hypothesis-generating pending randomized trials.
Observational (n=10)
No
Absolute Event Rate: 0.18% vs 0.29%
p-value: p=<0.05
An automated pattern recognition algorithm successfully identified recurrent spatiotemporal highest dominant frequency patterns in persistent AF, which exhibit higher organization and may represent potential ablation targets.
Li et al. (2021) conducted an observational in Persistent Atrial Fibrillation (n=10). High Dominant Frequency (HDF) mapping vs. Non-dominant patterns (non-DPs) was evaluated on Temporal standard deviation of mean dominant frequency (p=<0.05). Dominant patterns of high dominant frequency presented a lower temporal standard deviation (0.18 vs 0.29 Hz) and higher organization index compared with non-dominant patterns.
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