Key result
Depression and hypertension exhibit a bidirectional epidemiological association, potentially driven by sympathetic nervous system hyperreactivity and genetic influences.
This review highlights the bidirectional relationship between depression and hypertension, emphasizing shared pathophysiological mechanisms and the potential for antidepressants to disrupt blood pressure control.
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May prompt integrated depression screening in hypertension care; leaves open causal mechanisms and treatment effects.
Scalco et al. (2005) conducted a review in Hypertension and depression. Depression and hypertension exhibit a bidirectional epidemiological association, potentially driven by sympathetic nervous system hyperreactivity and genetic influences.
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