Key result
Depression, both untreated and treated, was associated with significantly better blood pressure control compared to no depression in hypertensive patients at high cardiovascular risk (OR 1.28 and 1.30, respectively).
Why the study?
Does depression influence blood pressure control in hypertensive individuals at high cardiovascular risk?
Cross-Sectional (n=5,954)
Yes
Does depression influence blood pressure control in hypertensive individuals at high cardiovascular risk?
Odds Ratio: 1.28 (95% CI 1.06–1.55)
Absolute Event Rate: 33.9% vs 26.5%
In hypertensive patients at high cardiovascular risk, a diagnosis of depression is paradoxically associated with better blood pressure control, potentially due to more frequent healthcare utilization or medication effects.
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Should not change hypertension management; hypothesis-generating for confounding by healthcare access in high-risk patients.
Mejía-Lancheros et al. (2014) conducted a cross-sectional in Hypertension at high cardiovascular risk (n=5,954). Depression (untreated or treated) vs. No depression was evaluated on Optimal control of blood pressure (SBP < 140 mmHg and DBP < 90 mmHg) (OR 1.28, 95% CI 1.06-1.55). Depression, both untreated and treated, was associated with significantly better blood pressure control compared to no depression in hypertensive patients at high cardiovascular risk (OR 1.28 and 1.30, respectively).
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