Echocardiographic Patterns of Pulmonic Valve Motion with Pulmonary Hypertension
Key result
Echocardiographic evaluation of the pulmonic valve in patients with pulmonary hypertension showed a significantly reduced diastolic (e-f) slope compared to normal subjects (5.2 vs 36.9 mm/sec, P<.001).
Why the study?
What are the echocardiographic patterns of pulmonic valve motion in patients with pulmonary hypertension compared to normal subjects?
Population
56 patients, comprising 24 normal subjects and 32 patients with pulmonary hypertension.
Comparison
Echocardiographic evaluation of pulmonic valve… vs Normal subjects
Design
Case-control
Authors
Discussion
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Member takes
Implication
May support noninvasive pulmonary hypertension detection via pulmonic valve echocardiography; leaves open prospective validation against catheterization.
Key Points
- To evaluate echocardiographic patterns of the pulmonic valve in normal patients versus those with pulmonary hypertension.
- Examined echocardiographic tracings in 24 normal patients and 32 patients with pulmonary hypertension.
- Assessed the presence and depth of the 'a' wave, diastolic slope, and occurrence of mid-systolic events.
- Analyzed right heart failure associations in patients with pulmonary hypertension.
- In pulmonary hypertension, 19 of 24 patients showed no 'a' wave; small 'a' waves were observed in five, all of whom had right heart failure.
- Diastolic slope was significantly reduced in pulmonary hypertension (5.2 ± 8.9 mm/sec) compared to normals (36.9 ± 25.4 mm/sec, P < .001).
- Mid-systolic closure or fluttering occurred in 18 of 20 patients with pulmonary hypertension, findings absent in normal patients.
Study Design
Type
Observational (n=56)
Structured PICO
What are the echocardiographic patterns of pulmonic valve motion in patients with pulmonary hypertension compared to normal subjects?
P
Population
56 patients, comprising 24 normal subjects and 32 patients with pulmonary hypertension (mean pulmonary artery pressure ≥20 mm Hg).
I
Intervention
Echocardiographic evaluation of pulmonic valve motion
C
Comparator
Normal subjects
O
Outcome
Echocardiographic parameters of pulmonic valve motion including presence and depth of 'a' wave, amplitude of valve opening, diastolic (e-f) slope, and mid-systolic closure or flutteringsurrogate
Main Result
Absolute Event Rate: 5.2% vs 36.9%
p-value: p=<.001
Echocardiographic evaluation of the pulmonic valve reveals distinct patterns, such as a reduced e-f slope, absent 'a' waves, and mid-systolic fluttering, which are indicative of pulmonary hypertension.
Cite This Study
Weyman et al. (1974) conducted an observational in Pulmonary Hypertension (n=56). Echocardiographic evaluation of the pulmonic valve vs. Normal subjects was evaluated on Diastolic (e-f) slope (p=<.001). Echocardiographic evaluation of the pulmonic valve in patients with pulmonary hypertension showed a significantly reduced diastolic (e-f) slope compared to normal subjects (5.2 vs 36.9 mm/sec, P<.001).