Key result
CMR and CECT noninvasively detect and quantify post-MI lipomatous metaplasia as an arrhythmogenic substrate.
Why the study?
Myocardial lipomatous metaplasia is increasingly reported post-MI and detectable noninvasively, but a synthesis of CMR and contrast-enhanced CT techniques and their clinical utility was needed.
How can cardiac magnetic resonance and computed tomography be used to noninvasively assess lipomatous metaplasia as an arrhythmogenic substrate in postinfarct patients?
How can cardiac magnetic resonance and computed tomography be used to noninvasively assess lipomatous metaplasia as an arrhythmogenic substrate in postinfarct patients?
This review highlights the utility of cardiac magnetic resonance and computed tomography in noninvasively detecting myocardial lipomatous metaplasia, which may serve as an important arrhythmogenic substrate in post-myocardial infarction patients.
May support noninvasive post-MI substrate imaging; leaves open prospective validation before clinical adoption.
Myocardial lipomatous metaplasia (LM) has been increasingly reported in patients with prior myocardial infarction. Cardiac magnetic resonance and cardiac contrast-enhanced computed tomography have been used to noninvasively detect and quantify myocardial LM in postinfarct patients, and may provide useful information for understanding cardiac mechanics, arrhythmia susceptibility, and prognosis. This review aims to summarize the advantages and disadvantages, clinical applications, and imaging features of different cardiac magnetic resonance sequences and cardiac contrast-enhanced computed tomography for LM detection and quantification. We also briefly summarize LM prevalence in different cohorts of postinfarct patients and review the clinical utility of cardiac imaging in exploring myocardial LM as an arrhythmogenic substrate in patients with prior myocardial infarction.
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Xu et al. (2023) conducted a review in Prior myocardial infarction. Cardiac magnetic resonance and cardiac contrast-enhanced computed tomography was evaluated. Cardiac magnetic resonance and contrast-enhanced computed tomography provide noninvasive detection and quantification of myocardial lipomatous metaplasia as an arrhythmogenic substrate post-infarction.
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