Key result
Combined LVAD and VA ECMO stabilizes incessant VF to enable successful heart transplantation.
Why the study?
Does combined LVAD and VA ECMO support improve hemodynamic stability and survival to transplant in a patient with LVAD and incessant ventricular fibrillation complicated by right heart failure?
Case Report (n=1)
Does combined LVAD and VA ECMO support improve hemodynamic stability and survival to transplant in a patient with LVAD and incessant ventricular fibrillation complicated by right heart failure?
Combined LVAD and VA ECMO can successfully bridge patients with LVAD-associated incessant ventricular fibrillation and right heart failure to heart transplantation.
May support combined LVAD-VA ECMO bridging in select refractory VF cases; leaves open safety and efficacy in larger cohorts.
Ventricular fibrillation, a life-threatening ventricular arrhythmia, may result in pulselessness, loss of consciousness and sudden cardiac death. In this case report, we describe our experience in managing a 54-year-old man with HeartMate3 left ventricular assist device (LVAD) as a bridge to transplantation due to dilated non-ischemic cardiomyopathy, presenting with incessant ventricular arrhythmia for 35 days despite multiple attempts to restore normal rhythm with external direct current cardioversion and anti-arrhythmic medications. The patient remained stable in ventricular arrhythmia with no progression to asystole, but hemodynamic collapse due to right heart failure occurred in the third week. Combined use of two mechanical circulatory support devices (LVAD with VA ECMO) was needed to achieve haemodynamic and metabolic stability, eventually leading to successful heart transplantation in the index admission. The patient was discharged home 2 weeks after transplantation in good clinical condition.
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Akel et al. (2022) conducted a case report in Ventricular fibrillation in LVAD patient (n=1). Combined mechanical circulatory support (LVAD with VA ECMO) was evaluated on Hemodynamic and metabolic stability leading to successful heart transplantation. Combined use of LVAD and VA ECMO achieved hemodynamic and metabolic stability in a patient with incessant ventricular fibrillation, leading to successful heart transplantation.
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