Why the study?
Does high depressive symptomatology increase the risk of stroke and cardiovascular-related mortality in older adults with diagnosed hypertension?
Population
Older adults with diagnosed hypertension from East Boston, Massachusetts; New Haven, Connecticut; and Iowa
Comparison
High depressive symptomatology vs Nondepressed counterparts
Design
Cohort
Follow-up
Between 1982 and 1988
Key result
High depressive symptomatology in older adults with hypertension was associated with a 2.3 to 2.7 times higher rate of stroke compared to nondepressed counterparts.
Authors
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May inform risk stratification in older hypertensives; leaves open whether treating depression reduces stroke risk.
Cohort
Yes
Does high depressive symptomatology increase the risk of stroke and cardiovascular-related mortality in older adults with diagnosed hypertension?
Effect estimate: RR 2.3-2.7
High depressive symptoms in older adults with hypertension are associated with a significantly increased risk of stroke and possibly cardiovascular-related death.
Simonsick et al. (1995) conducted a cohort in Hypertension. High depressive symptomatology vs. Nondepressed counterparts was evaluated on Blood pressure control, stroke, and cardiovascular-related mortality (RR 2.3-2.7). High depressive symptomatology in older adults with hypertension was associated with a 2.3 to 2.7 times higher rate of stroke compared to nondepressed counterparts.
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