Key result
Single echo beats without sustained conduction show comparable AVNRT recurrence to complete slow pathway ablation.
Why the study?
It was unknown whether the return of slow pathway conduction after acute elimination during cryoablation for AVNRT poses a risk for recurrence compared to standard ablation.
Does return of slow pathway conduction after elimination during cryoablation increase the risk of recurrent AVNRT in pediatric patients?
Cohort (n=44)
No
Does return of slow pathway conduction after elimination during cryoablation increase the risk of recurrent AVNRT in pediatric patients?
Recurrent single echo beats without sustained slow pathway conduction may be an acceptable endpoint for slow pathway cryoablation of AVNRT in pediatric patients.
Answers are grounded in this paper and cite their sources.
May support residual single echo beats as cryoablation endpoint in pediatric AVNRT; leaves open need for randomized confirmation.
BACKGROUND: Cryoablation for atrioventricular nodal reentrant tachycardia (AVNRT) is effective and safe with a reported limitation of lower success and higher recurrence rates. We have observed cases in which slow pathway conduction was eliminated as demonstrated by atrial extra-stimulus testing within 1 min of cryo-energy delivery but returned following tissue rewarming. Frequently, slow pathway conduction persisted despite multiple acutely successful lesions over a broad anatomic region. We aimed to determine if return of slow pathway conduction after elimination during cryoablation represents a risk for recurrent AVNRT with the same intermediate term results as slow pathway ablation. We hypothesize that remnant single echo beats in the absence of sustained slow pathway conduction and inducible AVNRT is an acceptable end point after clear slow pathway elimination during cryoablation. METHODS: Retrospective chart review of patients undergoing attempted slow pathway ablation for AVNRT using solely cryoablation between January 2015-January 2018. RESULTS: Forty-four patients met inclusion criteria with at-least 2 features of dual AVN physiology. 19 patients had return of slow pathway conduction shortly after clear elimination during cryoablation (Group A) while 25 did not (Group B). All in Group A had recurrent single echo beats but none had sustained slow pathway conduction at the end of the procedure nor AVNRT recurrence at 1 year. CONCLUSION: Recurrent single echo beats with absent sustained slow pathway conduction and non-inducible AVNRT may be an acceptable endpoint for slow pathway ablation of AVNRT using cryoablation when there is elimination of slow pathway demonstrated during energy delivery.
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Dasgupta et al. (2020) conducted a cohort in Atrioventricular nodal reentrant tachycardia (AVNRT) (n=44). Cryoablation with slow pathway modification (return of slow pathway conduction) vs. Cryoablation with complete slow pathway ablation (no return of slow pathway conduction) was evaluated on Recurrence of AVNRT at 1 year (p=1.000). Recurrent single echo beats with absent sustained slow pathway conduction after cryoablation resulted in 0% AVNRT recurrence at 1 year, comparable to 4% with complete slow pathway ablation.
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