Key result
Computed tomography imaging correlated with gross infarct weight (r=0.83) in isolated canine hearts, although it consistently underestimated infarct volume.
Why the study?
Does computed tomography accurately localize and size experimental acute myocardial infarcts compared to gross pathology in a canine model?
Population
20 isolated, arrested canine hearts with experimental acute myocardial infarcts produced by left anterior…
Comparison
Computed tomography imaging following… vs Gross infarct weight (pathological examination).
Design
Preclinical
Follow-up
24-72 hours postinfarction
Authors
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CT may refine experimental infarct models; leaves open clinical translation pending human validation.
Does computed tomography accurately localize and size experimental acute myocardial infarcts compared to gross pathology in a canine model?
Effect estimate: r=0.83
CT imaging demonstrates strong correlation with gross pathology for sizing acute myocardial infarcts in an experimental model, highlighting its potential for clinical evaluation.
Gray et al. (1978) studied Acute myocardial infarction (n=20). Computed tomography (CT) imaging vs. Gross infarct weight was evaluated on Correlation of infarct volume determined by CT with gross infarct weight (r=0.83). Computed tomography imaging correlated with gross infarct weight (r=0.83) in isolated canine hearts, although it consistently underestimated infarct volume.
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