Key result
Imaging confirms rare RV metastatic osteosarcoma 12 years post-diagnosis responding to surgical debulking and chemotherapy.
Case Report (n=1)
Multimodality imaging including TTE, cardiac CT, and cardiac MRI is effective in evaluating right ventricular masses and guiding management of rare cardiac metastases.
Supports multimodality imaging for rare RV metastases; leaves open standardized management in this entity.
The authors report a 27-year-old woman with a remote left femoral osteosarcoma and amputation above the left knee who presented with a large right ventricular mass. Initial evaluation with thoracic CT was inconclusive regarding thrombus versus tumor, but metastatic osteosarcoma was suggested by findings at transthoracic echocardiography, cardiac CT, and cardiac MRI. The patient underwent tumor debulking, and osteosarcoma was confirmed with pathologic examination. She responded to chemotherapy, which resulted in reduction in size of the residual right ventricular tumor and of a few pulmonary metastases. Following induction chemotherapy, patient remains well undergoing maintenance therapy with an oral tyrosine kinase inhibitor. Keywords: CT, Echocardiography, MR Imaging, Intraoperative, Cardiac, Heart, Right Ventricle, Imaging Sequences, Metastases, Oncology Supplemental material is available for this article.
No takes yet. Share an insight, caveat, or question.
Bannan et al. (2021) conducted a case report in Right ventricular mass (metastatic osteosarcoma) (n=1). Tumor debulking and chemotherapy was evaluated. Multimodality imaging and pathologic correlation confirmed a rare right ventricular metastatic osteosarcoma 12 years after initial diagnosis, which responded to surgical debulking and chemotherapy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: