Why the study?
Does daily treadmill training improve muscle performance, exercise tolerance, and muscle blood flow in rats with bilateral femoral artery stenosis?
Population
Rats with bilateral surgical stenosis of the femoral artery
Comparison
Daily treadmill training initiated 48 hours… vs Sedentary stenosed animals
Design
Preclinical
Follow-up
5 weeks
Authors
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May enhance muscle recovery in stenotic limbs; leaves open translation to human PAD therapy.
Does daily treadmill training improve muscle performance, exercise tolerance, and muscle blood flow in rats with bilateral femoral artery stenosis?
Treadmill training improves muscle function and exercise tolerance in a rat model of femoral artery stenosis, associated with more homogenous blood flow distribution within the muscle.
Mathien et al. (1986) studied this question.
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