June 1, 1997Microcirculation

Femoral Artery Ligation Stimulates Capillary Growth and Limits Training‐Induced Increases in Oxidative Capacity In Rats

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Population

Adult rats

Comparison

Right femoral artery ligation with or without… vs Left hindlimb and sedentary rats

Design

Preclinical

Authors

KRKarl C. RobertsSt George's, University of London CNCraig Nixon JUJoseph L. UnthankIndiana University School of Medicine

Discussion

Member takes

Implication

Suggests ischemia-exercise interactions may limit oxidative gains in rodent muscle; leaves open translation to human PAD.

Structured PICO

Population

Adult rats

Intervention

Right femoral artery ligation (LIG) with or without treadmill exercise training (TR)

Comparator

Left hindlimb (normally perfused control, NORM) and sedentary rats (SED)

Outcome

Capillary:fiber ratio, number of capillary contacts per fiber, and citrate synthase (CS) activity in the plantaris and soleus musclessurrogate

Femoral artery ligation induces capillary proliferation in specific hindlimb muscles and interacts with exercise training to limit oxidative capacity adaptations in rats.

Cite This Study

Roberts et al. (1997) studied this question.

synapsesocial.com/papers/6a85c16c3028043586c92cc3 https://doi.org/10.3109/10739689709146788

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Femoral Artery Ligation Stimulates Capillary Growth and Limits Training‐Induced Increases in Oxidative Capacity In Rats

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Femoral Artery Ligation Stimulates Capillary Growth and Limits Training‐Induced Increases in Oxidative Capacity In Rats

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider