Why the study?
Does exercise training reduce collateral or microvascular resistances in a rat model of arterial insufficiency?
Population
Rats with right femoral arterial ligation (age 10 wk) as a model of arterial insufficiency
Comparison
Treadmill training vs Sedentary control group
Design
Preclinical
Follow-up
7-9 weeks
Authors
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Exercise training may lower microvascular resistance without affecting collaterals in rat arterial insufficiency; leaves open translation to human peripheral artery disease.
Does exercise training reduce collateral or microvascular resistances in a rat model of arterial insufficiency?
Exercise training in a rat model of arterial insufficiency does not alter collateralization but may protect against acute occlusion by stimulating microvascular growth.
Lash et al. (1995) studied this question.
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