The renin-angiotensin system and blood pressure Differences between blacks and whites
Why the study?
Are there differences in plasma renin activity and serum ACE levels between blacks and whites, and how do they relate to blood pressure?
Population
293 individuals (110 blacks and 183 whites) who were not on antihypertensive medications
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Racial differences in renin activity and ACE-BP associations are hypothesis-generating; prospective studies needed before considering ethnicity in hypertension management.
Structured PICO
Are there differences in plasma renin activity and serum ACE levels between blacks and whites, and how do they relate to blood pressure?
P
Population
293 individuals (110 blacks and 183 whites) who were not on antihypertensive medications
C
Comparator
Whites compared to blacks
O
Outcome
Plasma renin activity, serum ACE levels, and their association with systolic and diastolic blood pressuresurrogate
While ACE levels are similar between blacks and whites, their association with blood pressure differs by race, suggesting underlying ethnic differences in blood pressure regulation.
Cite This Study
Jiang He (1999) studied this question.