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January 1, 2010Journal of Cardiovascular Disease Research1,609 citations

Excitation-Contraction Coupling and Cardiac Contractile Force

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DBDonald M. BersYZYujie Zhu

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This publication provides a comprehensive review of excitation-contraction coupling, cardiac action potentials, calcium fluxes, and the control of cardiac contractile force.

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Cardiac contractile force and excitation-contraction coupling

Abstract

Major cellular structures involved in E-C coupling. 2. Myofilaments: The end effector of E-C Coupling. 3. Sources and sinks of activator calcium. 4. Cardiac action potentials and ion channels. 5. Ca influx via sarcolemmal Ca channels. 6. Na/Ca exchange and the sarcolemmal Ca-pump. 7. Sarcoplasmic reticulum Ca uptake, content and release. 8. Excitation-contraction coupling. 9. Control of cardiac contraction by SR and sarcolemmal Ca fluxes. 10. Cardiac inotropy and Ca mismanagement. References. Index.

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Bers et al. (2010) conducted a review in Cardiac contractile force and excitation-contraction coupling. This publication provides a comprehensive review of excitation-contraction coupling, cardiac action potentials, calcium fluxes, and the control of cardiac contractile force.

synapsesocial.com/papers/6a0ee43b1c5e2d2319fa0b9ahttps://doi.org/10.1016/s0975-3583(10)11011-0
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