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December 1, 1999Cardiovascular ResearchOpen Access

Coming full circle Membrane potential, sarcolemmal calcium influx and excitation–contraction coupling in heart muscle

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Population

Heart muscle (single heart cells and multi-cellular preparations)

Design

Review

Authors

IHIon A. Hobai

Discussion

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Overview

Challenges standard Ca-dependent models of cardiac contraction; leaves open a potential Ca-independent release mechanism pending targeted experiments.

Structured PICO

P
Population
Heart muscle (single heart cells and multi-cellular preparations)

The review summarizes 20 years of experimental data on excitation-contraction coupling in heart muscle, suggesting the existence of a calcium-independent release mechanism.

Cite This Study

Ion A. Hobai (1999) studied this question.

synapsesocial.com/papers/6a70a8ccaf0c21e939286e4ehttps://doi.org/10.1016/s0008-6363(99)00236-9
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