Key result
Moderate-to-high intensity exercise increased arterial norepinephrine spillover to 13.52 nmol/min/m2 (P<0.01) and decreased clearance, compared to a smaller spillover rise during low intensity exercise.
Why the study?
Does exercise intensity and duration affect norepinephrine spillover and clearance in normal young subjects?
Population
25 normal young subjects
Comparison
Sustained upright bicycle exercise at low or… vs Baseline (pre-exercise) values
Design
Other
Follow-up
Up to 30 minutes
Authors
Loading...
Highlights intensity-dependent sympathetic spillover in healthy youth; leaves open translation to clinical populations or exercise prescriptions.
Does exercise intensity and duration affect norepinephrine spillover and clearance in normal young subjects?
Absolute Event Rate: 13.52% vs 3.14%
p-value: p=<0.01
During dynamic exercise, sympathetic nervous system activity is related to exercise intensity, with moderate-to-high intensity exercise causing a substantial rise in norepinephrine spillover and a small decrease in clearance.
Leuenberger et al. (1993) studied Healthy (n=25). Upright bicycle exercise vs. Baseline was evaluated on Arterial norepinephrine spillover (nmol.min-1 x m-2) (p=<0.01). Moderate-to-high intensity exercise increased arterial norepinephrine spillover to 13.52 nmol/min/m2 (P<0.01) and decreased clearance, compared to a smaller spillover rise during low intensity exercise.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: