Key result
Female gender was an independent predictor for atrial fibrillation recurrence after the first catheter ablation (HR 1.663; 95% CI 1.114-2.485; P=0.013) and had lower initial success (35.6% vs 57.1%).
Why the study?
Does female gender worsen the efficacy and safety outcomes of catheter ablation in patients with long-standing persistent atrial fibrillation?
Population
220 consecutive patients with long-standing persistent atrial fibrillation, including 73 females (33.2%)
Comparison
Catheter ablation in women vs Catheter ablation in men
Design
Cohort
Authors
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Women with long-standing persistent AF may warrant closer post-ablation monitoring; this observational association leaves open causal effects and needs prospective validation.
Cohort (n=220)
Does female gender worsen the efficacy and safety outcomes of catheter ablation in patients with long-standing persistent atrial fibrillation?
Effect estimate: HR 1.663 (95% CI 1.114-2.485)
p-value: p=0.013
In patients with long-standing persistent AF undergoing catheter ablation, women have lower initial success rates, higher recurrence risk, and more vascular complications compared to men.
ZHANG et al. (2013) conducted a cohort in Long-standing persistent atrial fibrillation (n=220). Female gender (undergoing catheter ablation) vs. Male gender was evaluated on Recurrence after the first catheter ablation (HR 1.663, 95% CI 1.114-2.485, p=0.013). Female gender was an independent predictor for atrial fibrillation recurrence after the first catheter ablation (HR 1.663; 95% CI 1.114-2.485; P=0.013) and had lower initial success (35.6% vs 57.1%).
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