What question did this study set out to answer?

The aim is to estimate analytical and biological variability of clinical chemistry analytes in elderly individuals.

Biological variability of 26 clinical chemistry analytes in elderly people.

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The aim is to estimate analytical and biological variability of clinical chemistry analytes in elderly individuals.
Analytical components of variation estimated from duplicate analyses of 10 specimens.
Samples collected from 27 healthy elderly subjects over 20 weeks.
Comparison of within-subject variations between elderly and younger subjects.
Biological variability does not increase with age alone.
Individuality observed in all analytes except serum water.
Critical differences for significant changes differ from those that prompt clinical action.

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Analytical study estimates variability in clinical chemistry analytes in elderly individuals, suggesting utility in clinical decision-making.

Fraser et al. (1989) studied this question.

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Analytical study estimates variability in clinical chemistry analytes in elderly individuals, suggesting utility in clinical decision-making.