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November 14, 2012Circulation Arrhythmia and ElectrophysiologyOpen Access

Critical sites for maintenance of postinfarct ventricular tachycardia were associated with >25% scar transmurality on LGE-CMR, and slow conduction sites with >75% scar transmurality.

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Population

23 patients with ischemic cardiomyopathy before ventricular tachycardia (VT) ablation

Design

Cohort

Key result

Critical sites for maintenance of postinfarct ventricular tachycardia were associated with >25% scar transmurality on LGE-CMR, and slow conduction sites with >75% scar transmurality.

Authors

TSTakeshi SasakiCMChristopher F. MillerRHRozann Hansford

Discussion

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Overview

May support LGE-CMR-guided targeting of postinfarct VT sites; hypothesis-generating for prospective outcome trials.

Study Design

Type

Observational (n=23)

Structured PICO

P
Population
23 patients with ischemic cardiomyopathy before ventricular tachycardia (VT) ablation
I
Intervention
Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) and electroanatomic mapping
O
Outcome
Associations among left ventricular wall thickness, postinfarct scar thickness, and intramural scar location on LGE-CMR, and local endocardial electrogram bipolar/unipolar voltage, duration, and deflections on electroanatomic mappingsurrogate

Critical sites for postinfarct VT maintenance are confined to areas with >25% scar transmurality on LGE-CMR, providing structural insights that may enhance MR-based ablation planning.

Cite This Study

Sasaki et al. (2012) conducted an observational in Ischemic cardiomyopathy (n=23). Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) and electroanatomic mapping was evaluated on Association between LGE-CMR scar characteristics and local electrograms. Critical sites for maintenance of postinfarct ventricular tachycardia were associated with >25% scar transmurality on LGE-CMR, and slow conduction sites with >75% scar transmurality.

synapsesocial.com/papers/6a0ef366a14f152feafa1011https://doi.org/10.1161/circep.112.970699
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of Nonischemic Scar Features on Local Ventricular Electrograms and Scar-Related Ventricular Tachycardia Circuits in Patients With Nonischemic Cardiomyopathy2013 · 66 citations
  2. 2Electroanatomic Characterization of Post-Infarct Scars2008 · 203 citations
  3. 3Noninvasive Electrocardiographic Imaging of Scar-Related Ventricular Tachycardia: Association With Magnetic Resonance Scar Imaging2018 · 1 citations
  4. 4Cardiovascular magnetic resonance determinants of ventricular arrhythmic events after myocardial infarction2021 · 36 citations
  5. 5Magnetic Resonance–Based Anatomical Analysis of Scar-Related Ventricular Tachycardia2007 · 204 citations