Key result
Primary aldosteronism was associated with significantly smaller blood pressure variability compared to essential hypertension in both supine and standing positions (P<0.05).
Why the study?
Does primary aldosteronism alter blood pressure variability and baroreflex sensitivity compared to essential hypertension and normotension?
Observational (n=139)
Does primary aldosteronism alter blood pressure variability and baroreflex sensitivity compared to essential hypertension and normotension?
Effect estimate: r = -0.397 to -0.457 (correlation)
p-value: p=<.05
Primary aldosteronism is characterized by decreased blood pressure variability compared to essential hypertension, which is partly explained by the preservation of baroreflex function.
Authors
No takes yet. Share an insight, caveat, or question.
Should not yet change practice; hypothesis-generating for baroreflex differences in primary aldosteronism.
Munakata et al. (1998) conducted an observational in Primary aldosteronism and essential hypertension (n=139). Primary aldosteronism vs. Essential hypertension and normotensive subjects was evaluated on Blood pressure variability (SD and CV of SBP and DBP) and baroreflex sensitivity (r = -0.397 to -0.457 (correlation), p=<.05). Primary aldosteronism was associated with significantly smaller blood pressure variability compared to essential hypertension in both supine and standing positions (P<0.05).
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