PulseTrendingJournal ClubResearchersJournalsExplore
Instagram
HomeTrendingJournal ClubExplore
Synapse
⌘+K
Synapse
December 8, 2007EP EuropaceOpen Access

Mechanical dyssynchrony by 3D echo correlates with acute haemodynamic response to biventricular pacing in heart failure patients

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does mechanical dyssynchrony measured by RT3DE correlate with acute hemodynamic response to biventricular pacing in heart failure patients?

Population

17 consecutive heart failure patients with symptomatic dilated cardiomyopathy, mean age 64 +/- 10 years, 8…

Comparison

Real-time 3D echocardiography to measure… vs Non-pacing mode

Design

Cohort

Follow-up

acute

Key result

Mechanical dyssynchrony measured by real-time 3D echocardiography significantly correlated with acute haemodynamic response to biventricular pacing (r = 0.729, P = 0.001).

Authors

JDJeroen van DijkPKPaul KnaapenIRIris K. Rüssel

Discussion

Loading...

Member takes

Overview

RT3DE dyssynchrony may aid responder prediction; leaves open its value for CRT selection pending prospective trials.

Study Design

Type

Observational (n=17)

Structured PICO

Does mechanical dyssynchrony measured by RT3DE correlate with acute hemodynamic response to biventricular pacing in heart failure patients?

P
Population
17 consecutive heart failure patients with symptomatic dilated cardiomyopathy, mean age 64 +/- 10 years, 8 male, 6 with ischaemic cardiomyopathy, mean QRS duration 136 +/- 32 ms, mean LVEF 31 +/- 10%.
I
Intervention
Real-time 3D echocardiography (RT3DE) to measure mechanical dyssynchrony (systolic dyssynchrony index of 17 LV segments, SDI17) during biventricular pacing
C
Comparator
Non-pacing mode
O
Outcome
Correlation between mechanical dyssynchrony (SDI17) and acute hemodynamic response (percentual change in dP/dt(max))surrogate

Main Result

Effect estimate: r = 0.729

p-value: p=0.001

Mechanical dyssynchrony measured by real-time 3D echocardiography significantly correlates with acute hemodynamic response to biventricular pacing in heart failure patients.

Cite This Study

Dijk et al. (2007) conducted an observational in Heart failure / Dilated cardiomyopathy (n=17). Real-time 3D echocardiography (RT3DE) and biventricular pacing vs. Non-pacing mode was evaluated on Correlation between systolic dyssynchrony index (SDI17) and percentual change in dP/dt(max) (r = 0.729, p=0.001). Mechanical dyssynchrony measured by real-time 3D echocardiography significantly correlated with acute haemodynamic response to biventricular pacing (r = 0.729, P = 0.001).

synapsesocial.com/papers/6a0efce42eca052da647fdaahttps://doi.org/10.1093/europace/eum262
View Full Paper
Ask AI
Bookmark
Share