Key result
Review summarizes feasibility, safety, and clinical outcomes of HPSD and vHPSD ablation for PVI.
Why the study?
Pulmonary vein isolation remains complex and time-consuming with unsatisfactory AF recurrence rates, triggering interest in high-power short-duration ablation.
Does high-power short-duration (HPSD) or very high-power short-duration (vHPSD) ablation improve outcomes and safety in patients undergoing pulmonary vein isolation for atrial fibrillation?
Does high-power short-duration (HPSD) or very high-power short-duration (vHPSD) ablation improve outcomes and safety in patients undergoing pulmonary vein isolation for atrial fibrillation?
This review summarizes the theoretical basis and current evidence for high-power short-duration (HPSD) and very high-power short-duration (vHPSD) ablation strategies in pulmonary vein isolation for atrial fibrillation.
Existing data support HPSD/vHPSD feasibility for PVI; leaves open superiority versus standard ablation in randomized trials.
Pulmonary vein isolation (PVI) is the cornerstone of atrial fibrillation (AF) ablation. However, this procedure remains complex and time-consuming, and the recurrence of AF after PVI is still unsatisfactory. Current technologies have improved our knowledge of the association between radiofrequency lesion creation and ablation parameters (power and duration), which triggered the development of high-power short-duration (HPSD). During the past decade, several preclinical and clinical studies have been conducted to confirm the feasibility, safety, and outcome of PVI ablation with HPSD or very high-power short-duration (vHPSD) settings, which increased electrophysiologists' interests in the utility of HPSD strategies. This paper describes the theoretical basis and recent research findings of HPSD or vHPSD ablation and summarizes the state-of-the-art evidence behind the role of this strategy in PVI.
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Qiu et al. (2020) conducted a review in Atrial fibrillation. High-power short-duration (HPSD) or very high-power short-duration (vHPSD) ablation was evaluated. This review summarizes the theoretical basis, feasibility, safety, and clinical outcomes of high-power short-duration and very high-power short-duration ablation for pulmonary vein isolation.
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