Key result
Very high-power short-duration ablation matches 50 W for preventing AF recurrence at one year.
Why the study?
Many patients require redo procedures after standard RFA for AF due to non-transmural lesions, leading to interest in comparing very HPSD to 50 Watt HPSD ablation guided by the CLOSE protocol.
Does very high-power short-duration ablation (90 W, 4 s) improve freedom from AF recurrence compared to a 50 W CLOSE approach in patients undergoing first-time pulmonary vein isolation?
Cohort (n=52)
Does very high-power short-duration ablation (90 W, 4 s) improve freedom from AF recurrence compared to a 50 W CLOSE approach in patients undergoing first-time pulmonary vein isolation?
p-value: p=0.37
Very high-power short-duration ablation (90 W, 4 s) for pulmonary vein isolation appears to offer comparable long-term efficacy to a 50 W CLOSE approach while reducing ablation time and radiation exposure.
No takes yet. Share an insight, caveat, or question.
May offer comparable one-year AF freedom; hypothesis-generating and requires randomized trials before adoption.
Seidl et al. (2022) conducted a cohort in Symptomatic atrial fibrillation (n=52). Very high-power short-duration (HPSD) ablation vs. HPSD CLOSE approach (50 Watts) was evaluated on Freedom from AF recurrence in a long-term ECG over a five days surveillance period (p=0.37). Very high-power short-duration ablation (90 W, 4 s) provided comparable efficacy for freedom from atrial fibrillation recurrence after one year compared to a 50 W approach (p=0.37).
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