Why the study?
Are onset age and severity of motor impairment associated with reduction of myocardial 123I-MIBG uptake in Parkinson's disease?
Are onset age and severity of motor impairment associated with reduction of myocardial 123I-MIBG uptake in Parkinson's disease?
Late onset and high severity Parkinson's disease are associated with greater myocardial sympathetic dysfunction as measured by reduced 123I-MIBG uptake.
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Later-onset, severe PD associates with greater myocardial sympathetic dysfunction; leaves open prognostic value of MIBG imaging.
K Hamada (2003) studied this question.
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