Key result
Percutaneous coronary intervention in patients with NSTE-ACS resulted in significantly lower 6-month mortality than predicted by the GRACE risk model for high-risk (12.6% vs 21.3%) and medium-risk (1.1% vs 5.0%) patients.
Why the study?
Does percutaneous coronary intervention reduce 6-month mortality compared to GRACE risk score predictions in patients with NSTE-ACS?
Cohort (n=690)
No
Does percutaneous coronary intervention reduce 6-month mortality compared to GRACE risk score predictions in patients with NSTE-ACS?
Absolute Event Rate: 12.6% vs 21.3%
p-value: p=0.0097
PCI in a high-volume center significantly reduces 6-month mortality compared to GRACE risk model predictions in medium and high-risk patients with NSTE-ACS.
May support PCI consideration in medium/high-risk NSTE-ACS; leaves open randomized confirmation versus GRACE predictions.
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Becker et al. (2014) conducted a cohort in non-ST elevation acute coronary syndrome (n=690). Percutaneous coronary intervention vs. GRACE risk model predicted mortality was evaluated on 6-month mortality in high-risk patients (p=0.0097). Percutaneous coronary intervention in patients with NSTE-ACS resulted in significantly lower 6-month mortality than predicted by the GRACE risk model for high-risk (12.6% vs 21.3%) and medium-risk (1.1% vs 5.0%) patients.
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