Why the study?
Traditional AMI clinical endpoints have limited utility in small-scale studies, and despite available methodologies to measure myocardial salvage index, their incorporation as clinical endpoints remains limited.
Design
Review
Authors
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MSI may inform surrogate endpoint selection in AMI trials; leaves open prospective validation of recommended CMR/SPECT methods.
The review recommends specific methodologies for measuring the myocardial salvage index using CMR and SPECT to serve as a sensitive surrogate clinical endpoint in AMI trials.
Zhao et al. (2024) studied this question.
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