What is the clinical evidence from this study?

Study design: Observational. Population: ST-segment elevation myocardial infarction (STEMI) (n=1147). Intervention: New risk scoring system for predicting no-reflow. Primary outcome: Prediction of no-reflow (AUC 0.809, 95% CI 0.772-0.842, p=< 0.001).

November 28, 2017Journal of Interventional CardiologyOpen Access

Prediction of no‐reflow and major adverse cardiovascular events with a new scoring system in STEMI patients

Q: What are the key findings of this study?

A new 7-variable risk score successfully predicted no-reflow in STEMI patients undergoing PCI, achieving an AUC of 0.809 (95% CI 0.772-0.842; P<0.001) in the derivation cohort.

View Full Paper

Ask AI

Bookmark

Key result

New 7-variable risk score predicts no-reflow in STEMI PCI with an AUC of ~0.81.

AUC 0.809
95% CI 0.772-0.842
P<0.001
n=1,147

Why the study?

Can a new scoring system accurately predict no-reflow and 1-year major adverse cardiovascular events in STEMI patients undergoing PCI?

Population

1,147 consecutive STEMI patients who underwent PCI

Design

Cohort

Follow-up

1-year

Authors

ABAdil Bayramoğlu HTHakan Taşolar AKAhmet Kaya

Discussion

Member takes

Overview

May support pre-PCI risk stratification in STEMI; hypothesis-generating pending external validation and outcome trials.

Study Design

Type

Observational (n=1,147)

Multicenter

Yes

Structured PICO

Can a new scoring system accurately predict no-reflow and 1-year major adverse cardiovascular events in STEMI patients undergoing PCI?

Population

1,147 consecutive STEMI patients who underwent PCI (515 in derivation cohort, 632 in external validation cohort from another center)

Intervention

A new 7-variable scoring system (age, EF ≤40, Syntax score ≥22, stent length ≥20, thrombus grade ≥4, Killip class ≥3, and pain-balloon time ≥4 h) to predict no-reflow

Outcome

Prediction of no-reflow and correlation with 1-year major adverse cardiac eventssurrogate

Main Result

Effect estimate: AUC 0.809 (95% CI 0.772-0.842)

p-value: p=< 0.001

A novel 7-variable risk score can effectively predict the development of no-reflow in STEMI patients undergoing PCI, potentially guiding pre-procedural management.

Cite This Study

Bayramoğlu et al. (2017) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=1,147). New risk scoring system for predicting no-reflow was evaluated on Prediction of no-reflow (AUC 0.809, 95% CI 0.772-0.842, p=< 0.001). A new 7-variable risk score successfully predicted no-reflow in STEMI patients undergoing PCI, achieving an AUC of 0.809 (95% CI 0.772-0.842; P<0.001) in the derivation cohort.

synapsesocial.com/papers/6a0f378e28dd8f49a2bdc862 https://doi.org/10.1111/joic.12463

View Full Paper

Ask AI

Bookmark

November 28, 2017Journal of Interventional CardiologyOpen Access

Prediction of no‐reflow and major adverse cardiovascular events with a new scoring system in STEMI patients

View Full Paper

Ask AI

Bookmark

Key result

New 7-variable risk score predicts no-reflow in STEMI PCI with an AUC of ~0.81.

AUC 0.809
95% CI 0.772-0.842
P<0.001
n=1,147

Why the study?

Can a new scoring system accurately predict no-reflow and 1-year major adverse cardiovascular events in STEMI patients undergoing PCI?

Population

1,147 consecutive STEMI patients who underwent PCI

Design

Cohort

Follow-up

1-year

Authors

ABAdil Bayramoğlu HTHakan Taşolar AKAhmet Kaya

Discussion

Member takes

Overview

May support pre-PCI risk stratification in STEMI; hypothesis-generating pending external validation and outcome trials.

Study Design

Type

Observational (n=1,147)

Multicenter

Yes

Structured PICO

Can a new scoring system accurately predict no-reflow and 1-year major adverse cardiovascular events in STEMI patients undergoing PCI?

Population

1,147 consecutive STEMI patients who underwent PCI (515 in derivation cohort, 632 in external validation cohort from another center)

Intervention

A new 7-variable scoring system (age, EF ≤40, Syntax score ≥22, stent length ≥20, thrombus grade ≥4, Killip class ≥3, and pain-balloon time ≥4 h) to predict no-reflow

Outcome

Prediction of no-reflow and correlation with 1-year major adverse cardiac eventssurrogate

Main Result

Effect estimate: AUC 0.809 (95% CI 0.772-0.842)

p-value: p=< 0.001

A novel 7-variable risk score can effectively predict the development of no-reflow in STEMI patients undergoing PCI, potentially guiding pre-procedural management.

Cite This Study

synapsesocial.com/papers/6a0f378e28dd8f49a2bdc862 https://doi.org/10.1111/joic.12463

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark