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April 1, 2015Clinical CardiologyOpen Access

A Risk Score for No Reflow in Patients With ST‐Segment Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention

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Why the study?

Can a 7-item simplified risk score accurately predict the risk of no-reflow phenomenon in patients with STEMI undergoing primary PCI?

Population

1,776 patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary…

Design

Cohort

Authors

JWJinwen WangZZZiqiang ZhouYCYunDai Chen

Discussion

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Overview

Hypothesis-generating for no-reflow risk stratification in STEMI; requires prospective validation before clinical adoption.

Structured PICO

Can a 7-item simplified risk score accurately predict the risk of no-reflow phenomenon in patients with STEMI undergoing primary PCI?

P
Population
1,776 patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) (training dataset n=912, test dataset n=864)
I
Intervention
A 7-item simplified risk score (age, pain-to-PCI time, neutrophil count, admission plasma glucose level, pre-PCI thrombus score, collateral circulation, and Killip class)
O
Outcome
Prediction of no-reflow (NRF) phenomenonsurrogate

A simple 7-item risk score can predict the incidence of no-reflow phenomenon with acceptable accuracy in STEMI patients undergoing primary PCI.

Cite This Study

Wang et al. (2015) studied this question.

synapsesocial.com/papers/6a70283984cc45bb7bdfb70ahttps://doi.org/10.1002/clc.22376
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Also Consider

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  1. 1Association between baseline neutrophil count, clopidogrel therapy, and clinical and angiographic outcomes in patients with ST-elevation myocardial infarction receiving fibrinolytic therapy2008 · 56 citations
  2. 2Angiographic No‐Reflow Phenomenon and Plaque Characteristics by Virtual Histology Intravascular Ultrasound in Patients with Acute Myocardial Infarction2007 · 37 citations
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  4. 4Impact of Microvascular Dysfunction on Left Ventricular Remodeling and Long-Term Clinical Outcome After Primary Coronary Angioplasty for Acute Myocardial Infarction2004 · 429 citations
  5. 5Short‐term Effect of Verapamil on Coronary No‐Reflow Associated With Percutaneous Coronary Intervention in Patients With Acute Coronary Syndrome: A Systematic Review and Meta‐analysis of Randomized Controlled Trials2013 · 39 citations