The European CRT Survey: 1 Year (9–15 Months) Follow-Up Results
Key result
In a European survey of successful CRT implantations, 81% of patients reported symptom improvement at 1 year, with a 24% rate of death or cardiovascular hospitalization.
Population
2,438 patients with successful cardiac resynchronization therapy implantation, including subgroups poorly…
Design
Cohort
Follow-up
~1 year (9-15 months)
Authors
Discussion
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Member takes
Implication
Supports real-world CRT use in diverse European patients; extends RCT findings to underrepresented subgroups.
Study Design
Type
Observational (n=2,438)
Multicenter
Yes
Structured PICO
P
Population
2,438 patients with successful cardiac resynchronization therapy (CRT) implantation, including subgroups poorly represented in randomized controlled trials (very elderly, prior device implantation, atrial fibrillation, and/or QRS duration <120 ms).
I
Intervention
Cardiac resynchronization therapy (CRT) implantation (CRT-P or CRT-D)
O
Outcome
Clinical outcomes including symptom severity, cardiovascular (CV) hospitalization, and survival at ~1 year (9-15 months) follow-upcomposite
Real-world European registry data demonstrates that successful CRT implantation is associated with significant symptom improvement and clinical outcomes consistent with randomized controlled trials, including in patient subgroups typically underrepresented in clinical trials.
Limitations
- Observational study design
- Outcomes in subgroup analyses must be interpreted with appropriate conservatism
- Only included successful CRT implantations
- Subgroup analyses must be interpreted with appropriate conservatism
Cite This Study
Bogale et al. (2011) conducted an observational in Heart failure (n=2,438). Cardiac resynchronization therapy (CRT) was evaluated on Death or cardiovascular hospitalization. In a European survey of successful CRT implantations, 81% of patients reported symptom improvement at 1 year, with a 24% rate of death or cardiovascular hospitalization.