Combined use of voltage limit adjustment and fast-Fourier transform analysis predicted ventricular tachycardia isthmuses with a sensitivity of 100% and a specificity of 80%.
Observational (n=9)
Does the combined use of VLA and fast-Fourier transform analysis accurately predict VT isthmuses in postinfarction patients undergoing catheter ablation?
Combining voltage limit adjustment with fast-Fourier transform analysis of bipolar electrograms during sinus rhythm accurately identifies VT isthmuses in postinfarction patients.
BACKGROUND: Several conducting channels of ventricular tachycardia (VT) can be identified using voltage limit adjustment (VLA) of substrate mapping. However, the sensitivity or specificity to predict a VT isthmus is not high by using VLA alone. This study aimed to evaluate the efficacy of the combined use of VLA and fast-Fourier transform analysis to predict VT isthmuses. METHODS AND RESULTS: VLA and fast-Fourier transform analyses of local ventricular bipolar electrograms during sinus rhythm were performed in 9 postinfarction patients who underwent catheter ablation for a total of 13 monomorphic VTs. Relatively higher voltage areas on an electroanatomical map were defined as high voltage channels (HVCs), and relatively higher fast-Fourier transform areas were defined as high-frequency channels (HFCs). HVCs were classified into full or partial HVCs (the entire or >30% of HVC can be detectable, respectively). Twelve full HVCs were identified in 7 of 9 patients. HFCs were located on 7 of 12 full HVCs. Five VT isthmuses (71%) were included in the 7 full HVC+/HFC+ sites, whereas no VT isthmus was found in the 5 full HVC+/HFC- sites. HFCs were identical to 9 of 16 partial HVCs. Eight VT isthmuses (89%) were included in the 9 partial HVC+/HFC+ sites, whereas no VT isthmus was found in the 7 partial HVC+/HFC- sites. All HVC+/HFC+ sites predicted VT isthmus with a sensitivity of 100% and a specificity of 80%. CONCLUSIONS: Combined use of VLA and fast-Fourier transform analysis may be a useful method to detect VT isthmuses.
Kuroki et al. (Sun,) conducted a observational in Postinfarction ventricular tachycardia (n=9). Combined use of voltage limit adjustment and fast-Fourier transform analysis was evaluated on Prediction of ventricular tachycardia isthmuses. Combined use of voltage limit adjustment and fast-Fourier transform analysis predicted ventricular tachycardia isthmuses with a sensitivity of 100% and a specificity of 80%.