Key result
High-frequency electrocardiography (1,000 cps) revealed that notching on the downstroke of leads X, V4, and V6 significantly separated patients with myocardial disease from normal patients (P<0.01).
Why the study?
Does expanding the frequency response of the electrocardiogram to 1,000 cps help identify primary myocardial disease?
Population
169 patients with myocardial involvement, compared to normal patients
Comparison
High-frequency electrocardiogram vs Normal patients
Design
Cross-sectional
Authors
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May support high-frequency ECG for myocardial disease detection; leaves open prospective validation before clinical use.
Observational (n=169)
Does expanding the frequency response of the electrocardiogram to 1,000 cps help identify primary myocardial disease?
p-value: p=<0.01
High-frequency ECG up to 1,000 cps can identify primary myocardial disease through QRS notching, which remains detectable even in the presence of bundle-branch blocks.
Reynolds et al. (1967) conducted an observational in Primary myocardial disease (n=169). High-frequency electrocardiogram (1,000 cps) vs. Normal patients was evaluated on Notching on the downstroke of leads X, V4, and V6 separating abnormal from normal patients (p=<0.01). High-frequency electrocardiography (1,000 cps) revealed that notching on the downstroke of leads X, V4, and V6 significantly separated patients with myocardial disease from normal patients (P<0.01).
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