Key result
Optimizing modifiable risk factors and antithrombotic therapy can prevent ~80% of strokes.
Why the study?
Does the management of modifiable medical and behavioral risk factors prevent stroke in at-risk patients?
Does the management of modifiable medical and behavioral risk factors prevent stroke in at-risk patients?
This review highlights that optimal management of modifiable medical and behavioral risk factors can prevent up to 80% of strokes.
Supports risk factor optimization in stroke prevention; leaves open prospective validation of specific regimens.
Stroke remains to be a leading cause of disability. However, optimal strategies can prevent up to 80% of strokes. A large body of evidence supports many strategies for primary and secondary prevention of stroke. The purpose of this paper is to highlight recent major advances for management of modifiable medical and behavioral risk factors of stroke. Specific studies are highlighted, including those related to atrial fibrillation (AF), hypertension, revascularization, hyperlipidemia, antiplatelets, smoking, diet, and physical activity. Effective strategies include the use of novel oral anticoagulants for AF, antiplatelet therapy, and intensive lowering of atherosclerosis risk factors.
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Sherzai et al. (2015) conducted a review in Stroke. Stroke prevention strategies was evaluated. Optimal strategies for managing modifiable medical and behavioral risk factors, including novel oral anticoagulants and antiplatelet therapy, can prevent up to 80% of strokes.
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