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July 26, 2017European Heart Journal - Cardiovascular ImagingOpen Access

Apical four-chamber longitudinal left ventricular strain in patients with aortic stenosis and preserved left ventricular ejection fraction: analysis related with flow/gradient pattern and association with outcome

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Why the study?

Does apical four-chamber longitudinal strain predict all-cause mortality in patients with moderate or severe aortic stenosis and preserved LVEF?

Population

582 patients with moderate or severe aortic stenosis and preserved left ventricular ejection fraction, mean…

Design

Cohort

Follow-up

mean 2.6 ± 0.2 years

Authors

ESErwan SalaünInterventional / Structural CardiologyACAnne‐Claire CasaltaAssistance Publique Hôpitaux de MarseilleEDErwan DonalCardiac Imaging

Discussion

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Member takes

Overview

May refine mortality risk stratification in moderate/severe AS with preserved LVEF; leaves open prospective validation before guiding decisions.

Structured PICO

Does apical four-chamber longitudinal strain predict all-cause mortality in patients with moderate or severe aortic stenosis and preserved LVEF?

P
Population
582 patients with moderate or severe aortic stenosis (AS) and preserved left ventricular ejection fraction (≥50%), mean age 74.3 ± 10.9 years.
I
Intervention
Apical four-chamber (A4-C) longitudinal strain (LS) measurement by two-dimensional speckle tracking
O
Outcome
All-cause mortalityhard clinical

Apical four-chamber longitudinal strain is an independent predictor of all-cause mortality in patients with moderate or severe aortic stenosis and preserved LVEF.

Cite This Study

Salaün et al. (2017) studied this question.

synapsesocial.com/papers/6a0f95ee2badbc352afe6293https://doi.org/10.1093/ehjci/jex203

Topics

Echocardiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of Myocardial Deformation With Outcome in Asymptomatic Aortic Stenosis With Normal Ejection Fraction2012 · 180 citations
  2. 2Impact of impaired myocardial deformations on exercise tolerance and prognosis in patients with asymptomatic aortic stenosis2008 · 200 citations
  3. 3Global Strain in Severe Aortic Valve Stenosis2012 · 161 citations
  4. 4Alterations in multidirectional myocardial functions in patients with aortic stenosis and preserved ejection fraction: a two-dimensional speckle tracking analysis2011 · 228 citations
  5. 5Paradoxical Low-Flow, Low-Gradient Severe Aortic Stenosis Despite Preserved Ejection Fraction Is Associated With Higher Afterload and Reduced Survival2007 · 964 citations