Key result
AF is linked to higher NT-proBNP levels versus sinus rhythm in acute ischemic stroke.
Why the study?
The study aimed to assess NT-proBNP levels in acute ischemic stroke patients according to clinical and radiological features and investigate its relationship with short-term clinical outcomes.
Does serum NT-proBNP level correlate with stroke subtype and short-term prognosis in patients with acute ischemic stroke?
Population
107 acute ischemic stroke patients and 24 age- and sex-matched control subjects
Comparison
Stroke patients across AF status and stroke subtypes vs control subjects
Design
Prospective cohort study
Follow-up
3 months
Authors
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NT-proBNP elevation may aid AF identification in acute ischemic stroke; leaves open added prognostic value beyond current tools.
Cohort (n=131)
Does serum NT-proBNP level correlate with stroke subtype and short-term prognosis in patients with acute ischemic stroke?
Effect estimate: r = 0.491
p-value: p=<0.001
Elevated NT-proBNP levels in acute ischemic stroke patients can help identify cardioembolic etiology and paroxysmal atrial fibrillation, and predict worse short-term functional outcomes.
Arslan et al. (2022) conducted a cohort in Acute ischemic stroke (n=131). Serum NT-proBNP measurement vs. Healthy controls and sinus rhythm group was evaluated on Serum NT-proBNP levels across clinical/radiological features and correlation with 3-month functional outcome (r = 0.491, p=<0.001). Serum NT-proBNP levels were significantly higher in acute ischemic stroke patients with paroxysmal or chronic atrial fibrillation compared to those with sinus rhythm (P < 0.001).
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