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June 1, 1991Journal of Hypertension

Suppressed aggression accelerates early development of essential hypertension

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Key result

Suppressed aggression emerged as a superimposed permissive factor for a steeper trajectory or acceleration of early development of hypertension in young adults.

Why the study?

Do baseline blood pressure, stress-induced blood pressure responses, and suppressed aggression predict the early development of essential hypertension in young adults?

Population

121 subjects (98 normotensive and 23 borderline hypertensive) of both sexes aged 18-24 years.

Design

Cohort

Follow-up

30 (+/- 4 s.d.) months

Authors

CPCharles PeriniUniversity Hospital of BaselFLFranco B. M llerUniversity Hospital of BaselFHFritz R. B hlerLong Beach Medical Center

Discussion

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Implication

Suppressed aggression may accelerate early hypertension onset in young adults; leaves open causal inference and intervention effects in prospective trials.

Study Design

Type

Cohort (n=121)

Structured PICO

Do baseline blood pressure, stress-induced blood pressure responses, and suppressed aggression predict the early development of essential hypertension in young adults?

P
Population
121 subjects (98 normotensive and 23 borderline hypertensive) of both sexes aged 18-24 years.
O
Outcome
Development of borderline or established hypertensionsurrogate

Suppressed aggression and baseline or stress-induced systolic blood pressure are significant predictors for the early development and acceleration of essential hypertension in young adults.

Cite This Study

Perini et al. (1991) conducted a cohort in Essential hypertension (n=121). Suppressed aggression and stress-induced cardiovascular responses was evaluated on Development of borderline or established hypertension. Suppressed aggression emerged as a superimposed permissive factor for a steeper trajectory or acceleration of early development of hypertension in young adults.

synapsesocial.com/papers/6a0f99a7d8c5cf602efceba7https://doi.org/10.1097/00004872-199106000-00004

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Factors associated with the development of stable hypertension in young borderline hypertensives1996 · 29 citations
  2. 2Noninvasive Ambulatory 24 h Blood Pressures and Basal Blood Pressures Predict Development of Sustained Hypertension From a Borderline State1993 · 19 citations
  3. 3Psychosomatic factors in borderline hypertensive subjects and offspring of hypertensive parents.1990 · 35 citations
  4. 4Predictors of future established hypertension and diurnal blood pressure variability in borderline hypertension.1983
  5. 5Cardiovascular characteristics in adolescents who develop essential hypertension.1981 · 241 citations