Key result
Borderline hypertensive subjects and offspring of hypertensive parents showed altered psychosomatic factors, elevated heart rates (p<0.001), and enhanced plasma norepinephrine (p<0.05) versus controls.
Why the study?
Are psychosomatic factors and sympathetic overactivity altered in young subjects with borderline hypertension or a family history of hypertension compared to healthy controls?
Population
123 subjects aged 18-24 years, including 24 patients with borderline hypertension, 50 age-matched…
Design
Cross-sectional
Authors
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May indicate early sympathetic and psychosomatic involvement in hypertension risk; hypothesis-generating and leaves causal role open for prospective study.
Observational (n=123)
Are psychosomatic factors and sympathetic overactivity altered in young subjects with borderline hypertension or a family history of hypertension compared to healthy controls?
p-value: p=<0.001
Psychosomatic factors and sympathetic overactivity are evident in young subjects at risk for hypertension, suggesting their involvement in the early phases of the disease.
Perini et al. (1990) conducted an observational in Borderline hypertension and genetic risk of hypertension (n=123). Borderline hypertension and family history of hypertension vs. Controls with no family history of hypertension was evaluated on Psychosomatic factors, circulatory and neurohormonal reactivity to mental and physical stressors (p=<0.001). Borderline hypertensive subjects and offspring of hypertensive parents showed altered psychosomatic factors, elevated heart rates (p<0.001), and enhanced plasma norepinephrine (p<0.05) versus controls.
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