Key result
In a Japanese cohort of patients with hypertrophic cardiomyopathy, the dilated phase (HR 6.482) and non-sustained ventricular tachycardia (HR 3.290) independently predicted sudden cardiac death-relevant events.
Cohort (n=293)
Yes
Effect estimate: HR 6.482
Absolute Event Rate: 29.4% vs 3.5%
p-value: p=0.001
In an aged Japanese HCM cohort, dilated-phase HCM and non-sustained ventricular tachycardia are independent risk factors for sudden cardiac death-relevant events.
In this HCM population in an aged Japanese community, the annual rate of SCD-relevant events was 1.0%. HCM developed to D-HCM in a considerable number of patients, and D-HCM and NSVT were shown to be independently associated with an increased risk of SCD-relevant events.
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Kubo et al. (2020) conducted a cohort in Hypertrophic cardiomyopathy (HCM) (n=293). Dilated phase of HCM (D-HCM) vs. Without D-HCM was evaluated on Sudden cardiac death (SCD)-relevant events (HR 6.482, p=0.001). In a Japanese cohort of patients with hypertrophic cardiomyopathy, the dilated phase (HR 6.482) and non-sustained ventricular tachycardia (HR 3.290) independently predicted sudden cardiac death-relevant events.
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