Key result
Enterovirus 68 isolates demonstrated poor growth at 37 degrees C and acid lability at pH 3.0 compared to echovirus 11, sharing biological properties with human rhinoviruses.
Population
Enterovirus 68 clinical isolates and control echovirus 11
Comparison
Partial nucleotide sequencing, growth at 33… vs Echovirus 11 (control enterovirus)
Design
Preclinical
Authors
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Hypothesis-generating for EV68 respiratory role; leaves open human confirmation and clinical relevance.
Observational (n=16)
Enterovirus 68 is primarily a respiratory pathogen that shares biological and molecular properties with both enteroviruses and rhinoviruses.
Oberste et al. (2004) conducted an observational in Respiratory illness (n=16). In vitro viral characterization vs. Echovirus 11 was evaluated on Viral growth at different temperatures and pH levels. Enterovirus 68 isolates demonstrated poor growth at 37 degrees C and acid lability at pH 3.0 compared to echovirus 11, sharing biological properties with human rhinoviruses.
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